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NCT, A Safety Study of Lirilumab in Combination With Nivolumab or in Combination With Nivolumab and Ipilimumab in Advanced and/or Metastatic Solid. Lirilumab (INN) is a human monoclonal antibody designed for the treatment of cancer. It binds to KIR2DL1/2L3. This drug was developed by Innate Pharma and. Based on the hypothesis that inhibition of KIR-receptor blockade with lirilumab, a specific monoclonal antibody targeting KIR2DL1/2/3, may improve response.

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A Safety Study of Lirilumab in Combination With Nivolumab or in Combination With Nivolumab and Ipilimumab in Advanced and/or Metastatic Solid Tumors. Description Product Specifications Citations Documents. Lirilumab ELISA for determination of Lirilumab in human serum, plasma and cell culture supernatant. Lirilumab is a type of immunotherapy; it does not directly attack the cancer cells itself but encourages the body's innate immune system to target and kill the.

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Lirilumab. Rohner et al, Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia. Based on the hypothesis that inhibition of KIR-receptor blockade with lirilumab, a specific monoclonal antibody targeting KIR2DL1/2/3, may improve response. Lirilumab is an anti-Killer cell immunoglobulin-like receptors (KIR) fully human monoclonal antibody being developed by Innate Pharma and Bristol-Myers.